Defending Champions ZESCO United will hope to cement their stay at the summit of the FAZ-MTN super division table when they host Konkola Blades on Saturday.
This will be in a Week 22 encounter at Levy Mwanawasa stadium in Ndola.
ZESCO are enjoying top form, after opening up a seven-point lead at the top of the table last weekend, following a 2-nil win over Red Arrows in Lusaka.
But Konkola Blades, number 12 on the table will be going into the match with their heads high after thrashing National Assembly 3 goals to nil last weekend.
Second placed ZANACO host struggling Nakambla Leopards at Sunset stadium, while National Assembly will be away to Nkwazi.
But the fixture of the weekend will see twelve-time league champions Nkana renewing their rivalry with Power Dynamos in an explosive encounter at Arthur Davies stadium in Kitwe.
Power Dynamos lie third on the table on 42 points, while Nkana are ninth, with 28 points.
At Independence stadium in Choma, Green Eagles welcome Red Arrows, while Lusaka Dynamos wil play Napsa Stars.
Mighty Mufulira Wanderers will be away to Forest Rangers, with Green Buffaloes battling it out against Nchanga Rangers at Independence stadium in Lusaka.